How do i know how much vitamin e should an average male take in middle age?

No more than 300iu!: Anything more than 300iu of vitamin e is overkill, and larger doses have been shown to be associated with higher mortality. Speculation, is that while essentil, it is a relatively week anti-oxidant, compared to tea, colored fruits and veggies, and too much will block out their more potent effects. Vitamin e is more than an anti-oxidant and has other functions. They should be met at 100iu or less!