While older antidepressants had potential adverse effects on cardiac conduction and could cause dangerous cardiac arrhythmias, SSRIs like Zoloft have not been shown to be such a potential problem in patients with conduction disturbances like bundle branch block & won't aggravate valvular abnormalities. It is considered one of the go to antidepressants in patients with cardiac disease & depression.
Answered 9/28/2023
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