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A member asked:
I am prone to getting severe cold sores and i am on prophylactic acyclovir because i work in a nicu. i had a sore on my wrist develop that looks exactly like a large cold sore is this even possible!? several tiny vesicles, nickel size lesion?
A doctor has provided 1 answer
New HSV outbreaks, either from new infection or from self-infection (medical term auto-inoculation) is extremely rare. So most likely the new problem isn't herpes. However, it should be tested with HSV PCR. If herpes is confirmed, or just to evaluate the reason you have particularly severe cold sores, see an infectious diseases specialist. You may also need testing for acyclovir resistant HSV.
Answered 7/29/2023
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