A member asked:

Im hla-b27 positive. i have symptoms of muscle cramping, stiffness, heaviness, numbness, and ache all over my body. can these symptoms be associated with being hla-b27 positive?

A doctor has provided 1 answer
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

HLA-B27 raises the risk of several health problems, chiefly ankylosing spondylitis (a kind of arthritis of the spine), reactive arthritis (which can be triggered by various infections), and several others. It's probably not the reason for the symptoms you report, but to be certain see a rheumatologist. Here's a helpful website: https://emedicine.medscape.com/article/1201027-overview Good luck.

Answered 6/17/2023

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