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A member asked:
It is safe to alternate a ppi and pepcid ac, every other day? i am trying to taper off the ppi as instructed by my doctor but with acid rebound i am nervous. so is it safe to alternate those every other day?
A doctor has provided 1 answer
Proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs) are used to treat gastroesophageal reflux disease (GERD) and other acid-related disorders. PPIs are more potent acid suppressors than H2RAs, but they also have a longer duration of action. However, long-term use of PPIs is associated with several adverse effects, increased risk of infections, fractures, and kidney disease.
Answered 6/7/2023
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