A member asked:

Hello, had an hiv-1/hiv-2 qualitative rna and hiv-1/hiv-2 antibodies and hiv-1 p24 antigen and an rpr, rfx qn rpr/confirm tp done at 28 days post exposure with a female unknown status. all came negative. do i need further testing?

3 doctors weighed in across 2 answers

Best to do a followup testng at 8 weeks post exposure. The 28 day tests are about 95% conclusive and so best to test again. Between now and then you need to avoid any exposure then do the retesting to be more conlcusive than 95% with a negative test. You need to also manage your lifestyle forever not to get potential exposure. Take care of yourself like it is the only body you have!

Answered 5/3/2023

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Dr. Hunter Handsfield answered

Specializes in Infectious Disease

The HIV antibody test, by itself, requires 8 weeks for conclusive results. However, the combination results you have at 28 days (antibody, antigen and RNA) is conclusive; no more testing is needed. But you could have another antibody test at 8 weeks if you would like the additional reassurance. However, the RPR was too early to rule out syphilis; test again 6 weeks or more after the exposure.

Answered 5/3/2023

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