You can take together or separately and you need to take zofran 2-3 times a day. Please note that prednisone may precipitate gastritis which can manifest as nausea then in that case you need to take medication to neutralize stomach acid such as antacid, H2 blocker (cimetidine or famotidine) or proton pump inhibitor (omeprazole or prevacid, etc.). Good luck.
Answered 4/15/2023
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