A member asked:

I have read that xarelto used with zoloft increases the risk of bleeding. is this the same for all ssris? thx?

A doctor has provided 1 answer
Dr. Samuel Galima answered

Specializes in Family Medicine

Agents with any antiplatelet properties, which includes SSRIs like Zoloft, may enhance the anticoagulant effect of Rivaroxaban (Xarelto). In other words, it may increase bleeding side effects. Caution and increased monitoring for bleeding is advised

Answered 4/9/2023

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