A member asked:

Why is it said that ttp patients who have less severe adamsts13 deficiency, have higher relapse rates and higher mortality?

A doctor has provided 1 answer
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

I am not sure your statement is correct. By Cleveland clinic website: "Factors that predict a higher risk of relapse include persistently severely decreased ADAMTS13 activity, positive inhibitor and high titers of autoantibodies to ADAMTS13 during symptomatic TTP. During clinical remission, persistence of autoantibodies also indicates increased risk". Take care.

Answered 3/25/2023

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