A member asked:

Hi, i have temporary script for tramadol(250 mg). i also take xanax 3 mg for panic attacks. how many hours i have to wait after taking 250 mg of tramadol to take xanax?

2 doctors weighed in across 2 answers

This combination of medications would never be approved by most physicians because of dangerous interactions, specifically central nervous system depression and sedation.

Answered 1/30/2023

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Dr. Daniel Ziegler answered

Specializes in Emergency Medicine

Both drugs are addictive meaning over time you develop a tolerance to the drug and require a bigger dose to have the same effect. Once you do have a tolerance then removing the drug will cause withdrawal symptoms. Without knowing how long and how often you've been taking 3 mg of Xanax we can't answer your question. In a novice Xanax 3 mg with or without tramadol 250 mg is dangerous

Answered 1/30/2023

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