Hello. if i take benadryl in the morning and quetiapine 50mg at night would they still interact? if i take them separately. i take 50mg of quetiapine for sleep and i need the benadryl for my chronic cystitis, probably ic. they say benadryl will help?

50% of the Benadryl dose will still be in your system at about 6 hours but the maximal dose is at about 4 hours. There will still be some interaction with Quetiapine. Since it's important for you to take Benadryl for your interstial cystitis would 25 mgs instead of 50 mgs of Benadryl be worth trying? Drowsiness,dizziness& confusion are the interaction symptoms to watch out for.