Can you take flexeril (cyclobenzaprine hcl) and oxycodone together? the flexeril (cyclobenzaprine hcl) is for my tmj and the oxycodone is for a ruptured cyst. help would be fabulous!

Drug mix: You really should be careful with these 2 medicines. Both of them have side effects of drowsiness and when taken together, the effects could be potentiated or worsened. The bigger issue is that oxycodone is a narcotic and could lead to suppressing your respirations. That would clearly be something you would want to avoid.

Maybe: Oxycodone is a very potent drug. And there is a concern about taking the two drugs together. The best person to talk with regarding interactions would be the pharmacist. They have the knowledge to advise you on this question.

Maybe: Depends on your tolerance. I have patients that do. I would be careful especially if you take xanax (alprazolam) as well.

Flexeril (cyclobenzaprine hcl) & oxycodone: You may take them together, but since they both have sedative properties, you should consult with your physician and consider reduced dosages of them.

Ask Doctors: Perhaps. Can have overlapping sedative effects. Best bet is to coordinate these 2 meds between the 2 different docs who are prescribing them.