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A 27-year-old male asked:

Anti-phospholipid syndrome. suspected dvt so bilateral ultrasound/d dimer ordered. d dimer was negative. ultrasound was normal expect it stated (paroneal veins not demonstrated in both legs.) how common is dvt in this area ? safe to rule out dvt?

2 doctor answers3 doctors weighed in
Dr. Silviu Pasniciuc
Internal Medicine 29 years experience
In general a negative D-dimer rules out DVT/PE, however in cases where the pretest probability is high it becomes hard to interpret. Best going forward would be to establish with a vascular surgeon that can escalate testing if clinical suspicion for acute DVT remains high. History as far as previous DVT’s is critical in this context.
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Dr. Gurmukh Singh
Pathology 51 years experience
Yes. A negative D-dimer is good test to rule out DVT. Lack of visualization of peroneal veins may be a developmental anomaly.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Nov 6, 2022

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