Dad has ttp and hus syndrome from e. coli that turned into toxins hes very lethargic. scans dont show brain damage. his brain isnt functioning well. have him on soliris - they did plasma. will he get any better? hes in hospital barely responsive?

With these dire conditions, aggressive and not common therapies which are needed to treat thrombotic thrombocytopenic purpura and hemolytic uremic syndrome with an e coli sepsis, I'd expect some delirium or dulled.mental status from your dad. Let's hope that he responds to his intensive treatment. He's receiving great up to date care.

Your description is worrisome but not hopeless by any means. It may take time to treat successfully and stabilize, but am impressed with the thoroughness of interventions. Agree with Dr. Colantino, but would add an EEG study to try to objectify brain physiology, as this would evaluate potential underlying seizure activity and the status of secondary effects on the brain.