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A member asked:
Why do some antipsychotics lower dopamine and inadvertently cause depression?
A doctor has provided 1 answer
Antipsychotics, especially the first-generation or typical antipsychotics, block dopamine receptors in the brain. Dopamine is a neurotransmitter which has a significant role in the pathophysiology of depression. These interactions explains depression could be one of the side effects of antipsychotics.
Answered 5/17/2022
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