HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

Will the number of dopamine receptors from antipsychotic usage and its withdrawal lower over time? i think all this extra dopamine is giving insomnia

A doctor has provided 1 answer

Down regulation: In theory, the use of any receptor-driven chemical stimulus over time will result in reduction, or down-regulation of those receptors, especially if the dose is increased.

Answered 5/21/2016

1.3k views

Thank

Related Questions

A member asked:

Is there any antipsychotic without many side effects? Fear withdrawals too. Insomnia akathisia muscle weakness joint pain all present previous antipsy

4 doctors weighed in across 2 answers

A member asked:

Why do some antipsychotics lower dopamine and inadvertently cause depression?

A doctor has provided 1 answer

A member asked:

If I stop taking geodon (ziprasidone) and many other antipsychotics in the past will I have even more dopamine than before? Will it lower eventually 2predrug levels

A doctor has provided 1 answer

A member asked:

Does dopa mucuna and l dopa cause people to loss weight because they are getting dopamine back that was blocked by antipsychotics?

A doctor has provided 1 answer

A member asked:

Do antipsychotics prevent you from feeling good? Maybe they dont want us to feel good? Maybe the med does this by blocking dopamine?

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

Can being on antipsychotics long term lower dopamine in the D2 receptors but raise dopamine in unblocked dopamine receptors due to extra receptors?
Does phosphatidylserine cause insomnia in sensitive individuals because of increased dopamine? I am sensitive to dopamine bc of antipsychotic usage
If placed on atypical antipsychotics, is it true that the patient grows up to 30%more dopamine receptors? If true for everyone, can they be removed
Can withdrawal from ssri, benzodiazepine, and antipsychotic create insomnia for over four weeks? Does medication make a condition worse than ever befo
Why do anti psychotics block dopamine receptors? Dosent dopamine make you feel relaxed? Seems like they do more harm than good.

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.