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A 32-year-old female asked:

I took the trigger shot (ovidrel) when my follicle was 19mm. my lh and estradiol were about to peak (13. i had an iui 2 days after my trigger shot. what would be the reasons why iui would fail in this case?

2 doctor answers2 doctors weighed in
Dr. Hiep Le
Dr. Hiep Leanswered
Nephrology and Dialysis 43 years experience
Assuming eggs are released as expected but due to tubal occlusion, an ovulated egg is unable to be fertilized by sperm or to reach the endometrial cavity. If sperms do reach an egg, they may not be able to penetrate the egg’s covering. Then if an egg is fertilized, two-thirds of all human embryos fail to develop successfully.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. John Berryman
Obstetrics and Gynecology 55 years experience
"IUI" simply increases the chance of pregnancy, but fertilization may not occur for a variety of reasons. Tubal obstruction will prevent access of sperm to the released egg. Ask your GYN physician about a hysterosalpingogram (HSG) if pregnancy attempts continue to be negative.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Mar 18, 2022


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