A member asked:

Is amyloidosis a possibility ? 60 yo previous blood tests creatine at 1.5, kappa 38, lambda 15, ratio 2.4 all other tests normal including no m protein in blood or urine. 6 months follow up creatine levels 1.2, kappa 25, lambda 15, ratio now 1.62.?

A doctor has provided 1 answer

Your first round of blood tests showed elevated kappa free light chains and a high kappa/lambda ratio raising suspicion of a plasma cell dyscrasia seen in AL amyloidosis or multiple myeloma. Your creatinine of 1.5 was high. If you also had anemia & elevated calcium I would favor a diagnosis of myeloma. However 6 months later results are within normal limits. ?A bone marrow biopsy in future

Answered 2/20/2022

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