A member asked:

I've had severe side effects of pupil dilation drops (difficulty moving arm and legs + lightheadedness, for about 2 hours) my doc said it's very rare happening (1/m), i want to know what exactly happened and does it has long term effect?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

I wonder if any doctor is able to explain this idiosyncratic reaction but I can assure you there will not be any long term effect.

Answered 1/27/2022

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It is extremely unlikely that there is any connection between "pupil dilation" drops (phenylephrine and tropicamide generally) and the symptoms you describe. The amount of the drop you absorb systemically is exceedingly small. You can reduce it even more with a technique called punctal occlusion. This is more likely a vasovagal response. You can pursue this farther with your internist.

Answered 1/29/2022

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