A member asked:

Dose taking pentoxifylline 400 mg 2 times per day and l arginine 1000 mg 2 times per day and cialis 5 mg one time per day is a wrong combination and can causes priapism because of high increase of nitric oxide ? or this combination is safe ?

A doctor has provided 1 answer
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

Priapism is a rare side effect of cialis. I am not sure you use L arginine for erectile dysfunction or for peripheral vascular insufficiency along with pentoxifylline. In theory, because L arginine can increase the blood flow to the penis so it can strengthen the effect of cialis or exacerbate the side effect. However, there is no reported interaction of these three medications that I can find.

Answered 1/23/2022

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