The dose you are taking will certainly reduce the risk of infection by 95% and you may be taking more of the drug than you need. You will not become resistant to the medication but the spirochetes may. This article may help you: https://www.medscape.com/answers/220563-82166/what-is-the-role-of-doxycycline-in-the-treatment-of-leptospirosis Best wishes
Answered 11/19/2021
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