A member asked:

Can natural iui with hcg trigger shot cause (severe) ohss? if yes, how to remove the risk?

3 doctors weighed in across 2 answers

I have never heard of a natural cycle with an HCG trigger leading to OHSS. I don't think it's possible. OHSS is by definition a side effect of ovarian stimulation which comes with certain medications like Follistim or Menopur (not HCG).

Answered 10/13/2021

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Very unlikely. I have never seen a report of this. We see OHSS after medical stimulation of the ovaries

Answered 10/14/2021

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