I have been taking sertraline for about 12 years. i have been taking 150 mg. for about 6 years. i want to switch to a natural solution like st. john's wart and maybe 5tp... do i need to taper or can i just start with st. john's and 5t?

As in any transition from prescription medication to more natural substances, I would recommend you work closely with your doctor. Prescription antidepressants like sertraline usually needs to be slowly tapered before considering a substitute medication or medications. If this is not done, you can experience some very uncomfortable side effects as your body withdraws from the medication.

Agree with Dr. Ellis. It is not a do it yourself matter. You need to consult with the doctor who prescribed the medication for a safe way to reduce the dose. Keep in mind that the so called "natural" treatment may not be effective. Wish you good health!