A member asked:

Can someone that has the mthfr gene with a history of blood clots, receive the covid 19 vaccine?

3 doctors weighed in across 2 answers

Extremely rare reports of pathologic clotting - almost exclusively with AstraZeneca and J&J vaccines. Suggest 1). Check with local doc 2). Would probably get (personal opinion) but Moderna or Pfizer only. Would probably take low dose ASA for several months thereafter.

Answered 8/5/2021

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Dr. Christine Hom answered

Specializes in Pediatrics

Thrombophilia, or the tendency to have blood clots, is of concern in COVID infection because of a risk for clots. This would exceed the risk from vaccine, where the cases are identified in 1/500,000 receiving the Johnson and Johnson one-dose vaccine. I would recommend taking Pfizer or Moderna. Would discuss with your hematologist.

Answered 8/5/2021

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