U.S. doctors online nowAsk doctors free
Floresville, TX
A 64-year-old female asked:

what does high ast of 129 mean?

2 doctor answers2 doctors weighed in
Dr. Robert Killian
General Practice 28 years experience
Liver is in trouble: The ast enzyme is one of the main liver enzymes used to monitor liver health. A level of 129 is most likely four times the normal and represents a very stressed liver that may be in trouble. The source of the damage that is occurring in this liver needs to be identified soon so that resolving the problem can be undertaken.
Dr. Amy Deeken
Pathology 20 years experience
Liver damage: Ast is an enzyme found in liver, heart, brain, skeletal muscle, and red blood cells. When there is damage to any of these types of cells, ast is released into the blood and causes elevation of the normal levels. The most common cause of elevation is liver damage which can be due to many different disease processes.

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
$30 per visit with
membership

Similar questions

CA
A 25-year-old member asked:

How can you lower your sgpt and sgot levels?

2 doctor answers6 doctors weighed in
Dr. Shaym Puppala
Internal Medicine 25 years experience
Address the reason: Stgp (= alt = alanine aminotransferase) & SGOT (=ast =aspartate aminotransferase), are commonly elevated in liver disease (sometimes muscle disease or other). If high, this suggests liver injury and it is important to treat underlying reasons. I tell my patients to stop alcohol and nutritional supplements as first step in finding out the reason for the elevation. Further workup may be needed.
CA
A 38-year-old member asked:

How can you normalize sgpt and sgot results?

2 doctor answers5 doctors weighed in
Dr. Scott Beede
Internal Medicine 32 years experience
Why are they up?: Elevated liver enzymes (sgpt, sgot, also called AST and alt) are signs of inflammation in the liver, but they do not tell you the cause. The treatment will depend on the cause. A few of the common causes are overuse of alcohol. Being overweight, certain medications, infections, autoimmune diseases, and metabolic diseases (copper or iron storage diseases). Further investigation is needed.
A 32-year-old member asked:

What is the significance of a high AST level?

2 doctor answers5 doctors weighed in
Dr. Shaym Puppala
Internal Medicine 25 years experience
Many possibilities: Ast (aspartate aminotransferase) is an enzyme made by liver & muscle which when damaged can leak AST into the bloodstream more than normally. In addition to liver injury (eg from alcohol, overdoses of meds like acetaminophen, viral hepatitis, med side effects, hemochromatosis, fatty liver), AST can be high occur in thyroid disease, adrenal insufficiency, muscle disease. Sometimes no cause is found.
A 39-year-old female asked:

Can I trust the results of my tibc, alt(sgpt), ast(sgot) if it states afterwards hemolyzed result may be affected, and what would have caused it?

2 doctor answers6 doctors weighed in
Dr. Gregory Hines
Family Medicine 24 years experience
No: Any hemolyzed sample has sat at the lab or office too long, and the red blood cells have broken apart, releasing their contents. Any reading from such a sample is suspect, and should be repeated.
A 39-year-old member asked:

How can I lower levels of AST (sgot) and ALT (sgpt)?

1 doctor answer2 doctors weighed in
Dr. Michael Zevitz
Internal medicine 37 years experience
Depends on the cause: Sgot and SGPT are liver enzymes. Lowering them depends on the cause of the elevation. Some medications can cause the elevation and stopping the medications will result in normalizing them. Alcohol, gallstones, infections (mono, hepatitis), and other liver toxins can also cause elevated liver enzymes.

Related questions

A 42-year-old member asked:
1 doctor answer5 doctors weighed in
A 63-year-old female asked:
2 doctor answers2 doctors weighed in
A 46-year-old member asked:
1 doctor answer2 doctors weighed in
A 38-year-old member asked:
1 doctor answer3 doctors weighed in
A 40-year-old member asked:
1 doctor answer2 doctors weighed in

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
$30 per visit with
membership
Last updated May 1, 2018

People also asked

Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
$30 per visit with
membership

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.