Why streptomycin should not be administered in patients with myasthenia?

Effect on junction: Streptomycin is one of the aminoglycosides which is a class of anitbiotics that affects the neuromuscular junction. This is the area involved in myasthenia gravis. More specifically streptomycin can block the acetylcholine receptor and can also prevent the release of acetylcholine. See more at: http://archive.Ispub.Com/journal/the-internet-journal-of-neurology/volume-10-number-2.