A member asked:

Do you know what effects the drug quetiapine may have on cortisol levels?

A doctor has provided 1 answer
Dr. Yvette Kratzberg answered

Specializes in Pediatrics

An NIH study showed that a significant reduction of nocturnal cortisol excretion following quetiapine reflects a decreased activity of the hypothalamic–pituitary–adrenal-axis in healthy subjects. This may actually be the cause of many of the neuroendocrine side effects seen with this medication.

Answered 5/18/2021

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