Claritin vs zyrtec which works better for seasonal allergies?

This is defined by your own unique genetics. I find fexofenadine works better than either of these. Zyrtec (cetirizine) is a bit sedating to most, Claritin (loratadine) is the cheapest in generic form. Try them all & you'll decide what works for you.

In general, Zyrtec is more potent. If the sedation side effect from Zyrtec is an issue, try the Claritin