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A member asked:

Today i was having really bad cramps so i took one aleve. i then got the j&j vaccine two and a half hours later. did i ruin the vaccine? i know youre not supposed to take pain medication beforehand and ive been so stressed about this all day?

3 doctors weighed in across 2 answers

Absolutely not ! Even though you've read about it, it's been overstated and there aren't studies in humans that confirm a negative effect on the efficacy of the vaccine from taking NSAIDs

Dr Rhoads and another doctor agreed

Answered 3/12/2021

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Thank

Aleve is a low dose anti-inflammatory and is not either immunosuppressive or immunomodulatory. Your vaccine was not affected.

Answered 3/12/2021

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Thank

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