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A 21-year-old female asked:

I've been having urticaria, it appears out of nowhere for no reason and it refuses to be treated. i used loratadine and fexofinadine, yet both failed miserably. i've been suffering for more than 2 weeks. it's all over my body now. help me pls?

1 doctor answer2 doctors weighed in
Dr. Lauren Bickel
Specializes in Family Medicine
Hard to treat: Persistent urticaria can be hard to treat & has many causes including stress (but up to 50% of the time no cause is found). Adding Pepcid (famotidine, a histamine blocker, very safe & inexpensive) to an antihistamine like loratidine, plus possibly a round of prescription steroids, can help, as well as topical anti itch meds & oatmeal baths. Keep looking for possible triggers & do stress management
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Last updated Feb 19, 2021

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