Based on the current information on covid-19 vaccine, when is your best guess of when we can stop wearing masks and social distancing?

We still have a long way to go: We'll be able to stop wearing masks and social distancing when enough people are immune and unable to spread the virus. To reach this "herd immunity" will require a significant proportion of the population to be vaccinated. The exact proportion required to achieve herd immunity depends on how strictly people follow pandemic restrictions. In areas where people are not masking and social distancing, at least 75%, but preferably more than 85% of the population will need to be immune. Reference: https://www.nature.com/articles/d41586-020-02948-4

COVID 19: Excellent input from Dr. Rutledge. I agree. I think the effort will need to nationalized. Currently only a small percentage of the available COVID 19 in the US has actually been dispensed to people. There is only vaccine currently available for a small percentation of our population in the US. Many are resistant to being vaccinated. We are a long way off from stopping transmission precautions