A member asked:

I am currently taking paxil 40 mg. my new psychiatrist wants to put me on pristiq (desvenlafaxine) in addition. will this make me feel better?

4 doctors weighed in across 2 answers
Dr. Alan Ali answered

Specializes in Psychiatry

Paxil (paroxetine): 1 is ssri and 1 is snri. Your prescribing doctor would be the best to consult.

Answered 4/16/2013

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No: Paxil increase serotonin, Pristiq (desvenlafaxine) increase serotonin and norepinephrine. You can overload on serotonin and have a severe and life threatening reaction called serotonin syndrome.

Answered 6/30/2014

4.9k views

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