A member asked:

Does drinking a lot of water slow cyst development in polycystic kidney disease patients?

3 doctors weighed in across 2 answers

No: Nothing has been proven to slow cyst development. There are drugs undergoing trials; octreotide, Everolimus and tolvaptan all working on different systems that are promising. Adpkd patients are told to drink fluids to decrease the risk of stone formation and utis, the kidneys are very large urine collects in larger areas with slower flow making these complications more likely.

Answered 7/15/2018

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Pkd: YES. Vasopressin is a natural hormone that promotes cyst enlargement. High fluid intake daily suppresses vasopressin and reduces cyst enlargement. Aim for 4-6 liters per day. Avoid caffeine.

Answered 7/15/2018

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How much water per day shall i drink with stage 3 kidney disease?

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