I have acanthosis nigricans on elbows. my elbows hurt just if they touch anything. any meds or creams to help this? i'm 5'10/ 200 lbs, bs always ok

Skin is thick: Two issues: the disorder is caused by skin thickening, not pigment, so prescription creams that thin the thickened stratum corneum are generally helpful. Secondly, an md should evaluate you for potential causes. In some cases it runs in families, but in some cases related to underlying health issues. See a good dermatologist and you'll get relief and explanations about why in your case.