A member asked:

Any non-retinol based creams that might work for underarm acanthosis nigricans?(related to weight fluctuations and pcos)

2 doctors weighed in across 2 answers

Lactic acid : Lactic acid containing moisturizers may help to smooth the skin and reduce the appearance of the darkened areas.

Answered 6/26/2014

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Acanthosis nigricans: Treating the underlying cause of acanthosis nigricans (an) often helps decrease the discoloration and thickening of the skin, like weight loss, control of diabetes, adrenal problems, etc. Alpha hydroxy acid based creams are helpful for treating an on the neck and hands. They may be too irritating for underarms and lead to more discoloration. Also, making an in underarms mushy may increase odor.

Answered 6/24/2014

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