Probably refers to..: When a person's leukemia changes from a somewhat stable, chronic phase of the blood cancer, into a rapidly progressive phase in which the cancerous blood cells have changed and reproduce much more rapidly, thus becoming higher and higher in number... eventually leading to the patient's demise. This article explains: https://pdfs.semanticscholar.org/7b06/d93cd44a6921de35a61c915d9fc42f70a09d.pdf
Answered 10/24/2019
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