4-6 weeks: Almost all (~98%) of people with new HIV infections have positive HIV antigen-antibody (AgAb, "duo", 4th generation) tests by 4 weeks, and a negative result at that time is very reassuring. But on rare occasions it takes up to 45 days (6 weeks). Although official guidelines from many agencies still suggest waiting 3 months, most experts agree that advice is outdatted and 6 weeks is conclusive.
Answered 4/20/2023
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