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Tampa, FL
A 37-year-old male asked:

Is indomethacin 50 mg or diclofenac 75 mg better for knee, back, ankle, hands, and neck oa? i'm trying to find which one is better for pain.

2 doctor answers5 doctors weighed in
Dr. Kathy Robinson
Family Medicine 32 years experience
Depends on person: Diclofenac and indomethacin are both non-steroidal anti-inflammatory drugs (NSAIDs). One is not necessarily better for pain than the other but some patients do get more relief from one or the other of them. You just need to try them and see which works best for you. You also need to know that all NSAIDs may cause ulcers or kidney damage if used at high dosage or for long times. Talk to your Dr.
Dr. Charles Turck
Pharmacology 17 years experience
Possibly diclofenac: Normally, a person with osteoarthritis starts with acetaminophen. If he’s progressed past that or is ineligible, then diclofenac, indomethacin, or other drugs in their class (NSAIDs) may be appropriate. Of these, *diclofenac* may be a better option for some people because it may be associated with a lower risk of gastrointestinal side effects.

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Last updated Jul 11, 2019

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