Genetic disease: Alkaptonuria is a rare inherited disorder. It occurs when your body can’t produce enough of an enzyme called homogentisic dioxygenase (HGD). This enzyme break down a toxic substance called homogentisic acid. When you don’t produce enough HGD, homogentisic acid builds up in your body, the bones & cartilage becomes discolored/brittle, Urine that turns Brown or black when exposed to air
Answered 1/27/2019
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