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A 25-year-old male asked:

What are the possible causes of urine turning black on standing and exposed to air? provided that the urine was normal colored when passed ?

1 doctor answer3 doctors weighed in
Dr. Shaban Faruqui
Specializes in Gastroenterology
Genetic disease: Alkaptonuria is a rare inherited disorder. It occurs when your body can’t produce enough of an enzyme called homogentisic dioxygenase (HGD). This enzyme break down a toxic substance called homogentisic acid. When you don’t produce enough HGD, homogentisic acid builds up in your body, the bones & cartilage becomes discolored/brittle, Urine that turns Brown or black when exposed to air
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Last updated Jan 27, 2019

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