Is it safe to take gaperpentin pain killers when you have a heart murmur?

Likely ok: It is generally safe. None the less given the lack of medical history available I would suggest you talk to your PCP or Cardiologist (if you have one) about your case in particular.

Heart murmur/Gabapen: Heart murmur may be • Normal • Due to a medical condition:  High Blood Pressure  Anemia  Overactive Thyroid or due to • Heart valve problem. Gabapentin is a medication for nerve pain or seizure disorder Side effects of Gabapentin may be hypertension or peripheral Oedema. Please see a Cardiologist for Diagnosis and Treatment.