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A 47-year-old female asked:

What's small cd5 positive b cell population representing 0.4% of total leukocytes?

1 doctor answer • 1 doctor weighed in
Dr. Nancy Mckinney
Dr. Nancy Mckinneyanswered
Hematology and Oncology 21 years experience
Likely nothing: Monoclonal B cell lymphocytosis is a small population of malignant lymphocyte in the blood. A level of 0.4% is tiny, and likely not going to turn into anything bad. However, these cells are the type that make up chronic lymphocytic leukemia (in far higher numbers)and small lymphocytic lymphoma. It would be good to rule out lymphoma, and follow blood counts every 3-6 months. No treatment needed.
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