Is it okay to take cipro (ciprofloxacin) while on wellbutrin?

Drug Interaction: Yes. Of course. You should realize that your pharmacist at the very least would not have let you leave the pharmacy if this was a problem.

Probably: Both wellbutrin & Cipro (ciprofloxacin) can lower seizure threshhold in dose-dependent ways, so caution is advised when using them simultaneously. However, both your prescribing physician and the pharmacist know your medication doses, can assess your safety with them, and advise you reliably. Please ask your physician and/or pharmacist about your concerns.