If tlc is 3400/cm and esr is 48 is there problem??

Need more info: Do you have any symptoms? Why were these tests done? All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. Get HPV vaccine, if you are under 27 years of age.

Possibly.: The ESR is a possible indicator of inflammation in the body. It is not specific for anything, but it is often an indicator that something is wrong. I think with this evidence you probably should see your doctor and have a more thorough check up performed. At least talk about it with him or her. Good luck.