How dangerous is accutane. does it really cause permanent joint damage and gi problems like ibs? can side effects be permanent?

Worth the risk: The claimed link to inflammatory bowel disease -- which I thought was just bad studies -- was laid to rest by a meta-analysis in 2016; anyone still talking should know this. The arthritis is rare and we know little about it -- whether it's cause and effect is unsettled. Acne is a grave social and professional liability. If you need this Rx, go for it with close guidance.