A member asked:

Can i take 500mg methocarbamol with my usual 20mg nortriptyline for an unusually bad attack of trigeminal neuralgia? i have a dr appmt in 6 days

2 doctors weighed in across 2 answers
Dr. Heidi Fowler answered

Specializes in Psychiatry

Drug interactions.: Per Drugs.Com drug interaction checker there is possibility of moderate interaction. "Using nortriptyline together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination." See:

Answered 5/24/2017

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Not advised: Because both drugs are nervous system depressants, there is a potential for at least an additive effect. Spacing out the medications and avoiding activities like driving or operating machinery would be a start.

Answered 5/24/2017

683 views

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