A 56-year-old female asked:
can i take 500mg methocarbamol with my usual 20mg nortriptyline for an unusually bad attack of trigeminal neuralgia? i have a dr appmt in 6 days
2 doctor answers

Dr. Heidi Fowler answered
25 years experience Psychiatry
Drug interactions.: Per Drugs.Com drug interaction checker there is possibility of moderate interaction. "Using nortriptyline together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination." See:
Answered on May 24, 2017
1
1 comment

Dr. Heidi Fowler commented
25 years experience Psychiatry
Provided original answer
https://www.drugs.com/interactions-check.php?drug_list=1588-0,1734-0. This does not mean you can't take them together - but I always recommend you discuss it with your physician first.
May 24, 2017

Dr. Bert Liang answered
Specializes in Neurology
Not advised: Because both drugs are nervous system depressants, there is a potential for at least an additive effect. Spacing out the medications and avoiding activities like driving or operating machinery would be a start.
Answered on May 24, 2017
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