Markedly enlarged, vs mild, moderately or severe....where does markedly fall on the 'scale'?

Relative: This question needs some context to be able to answer it. If you let us know what the organ or structure is - we may be able to provide useful info.

What is enlarged?: There is no uniform scale for these descriptive terms. It would be better to measure the mass, lump, organ or lesion etc. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex.

Not certain.: Probably somewhere near severe. These words are not an exact science. Whatever you are talking about can be measured precisely, however. Good luck.