What is the cause of a charlie horse in my sleep that wakes me up with a lot of pain in my ankle and i feel like it is paralyzed. i can't even move it?

Unknown cause: Charlie horse leg pain is common and the cause is unknown. If you have these frequently you can lower the incidence by using quinine infused seltzer water in the late evening.

Could be a few thing: You need to see your doctor for testing. There are a few things that can cause your issue. Go get checked out

Nocturnal leg cramps: It's not completely clear. We used to use quinine tablets until the government decided you could only use that for malaria. I don't believe it is a wise decision. I recommend sometimes people try magnesium, as this may help. You also should stretch your leg night. This extension can help protect your leg