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A 63-year-old male asked:

Many people with cancer loose a lot of weight. is it because of lack of appetite (chemo) and that cancer is "eating" inside organs. please explain.

1 doctor answer1 doctor weighed in
Dr. Gurmukh Singh
Pathology 51 years experience
Multiple factors: Loss of appetite and increase in basal metabolism due to release of cytokines are the major reasons. Chemo and radiation treatments cause further weight loss by affecting digestion and food absorption. Depression in cancer patients is an additive factor.
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Last updated Apr 14, 2017


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