Complete appetite loss in chemo for metastic colon cancer , does not feel like eating anyting . is this unusual ?

No: Loss of appetite during chemotherapy is very common, and can last for days to weeks. There are some medicines that can help sometimes with that, but sometimes a feeding tube is necessary in severe cases.

Yes: Sadly yes a lot of cancer cause appetite loss even without the side effects of chemo. That's why people think that smoking marijuana which has it's own side effect of giving you the "munchies" would help cancer pt eat better. I think cancer pt's should be allowed whatever they need especially if they are in pain and need help should have access to whatever makes them feel better.