A 27-year-old male asked:
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when the spermatogonial stem cell get mutated by chemicals, if the mutated sperm fertilize the egg, will the child have de novo genetic defect?

1 doctor answer
Dr. Michael Traub
18 years experience Fertility Medicine
No: So lots of things cause mutations in sperm and most sperm are not good. That is why it takes millions to get one good sperm. When mutations occur they usually render the sperm less useful and normally that sperm is not going to fertilize and egg
Answered on Mar 6, 2017
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A 27-year-old male asked:
Dr. James Ferguson
45 years experience Pediatrics
Probably does happen: This is less likely to happen than fertilization by a healthy sperm. One of the features of male reproduction that differs from that of the female is ... Read More
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A 16-year-old female asked:
Dr. James Ferguson
45 years experience Pediatrics
No: It doesn't happen. As soon as sperm #1 joins the egg it is no longer receptive to any others. If by some freak accident it happened the mix would shed ... Read More
A 24-year-old male asked:
Dr. Clarence Grim
56 years experience Endocrinology
Sperm stem cells: Yes might be in the future. Right now would get sperm donor.
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A 40-year-old female asked:
Dr. Firas Barakat
Specializes in Internal Medicine
Only the last: Egg will be their for 24 hours sperm also will last may be a day.

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